Perinatal outcome of pregnancies complicated by diabetes and by maternal daily hyperglycemia not related to diabetes - A retrospective 10-year analysis

Citation
Mvc. Rudge et al., Perinatal outcome of pregnancies complicated by diabetes and by maternal daily hyperglycemia not related to diabetes - A retrospective 10-year analysis, GYNECOL OBS, 50(2), 2000, pp. 108-112
Citations number
20
Language
INGLESE
art.tipo
Article
Categorie Soggetti
da verificare
Journal title
GYNECOLOGIC AND OBSTETRIC INVESTIGATION
ISSN journal
0378-7346 → ACNP
Volume
50
Issue
2
Year of publication
2000
Pages
108 - 112
Database
ISI
SICI code
0378-7346(2000)50:2<108:POOPCB>2.0.ZU;2-A
Abstract
We analyzed the perinatal outcome of 1,086 pregnancies classified according to the response to the 3-hour 100-gram glucose tolerance test and the diur nal glycemic profile into the Rudge groups corresponding to control pregnan t women, class A gestational diabetic women, class A/B to FRH pregnant wome n and women with daily hyperglycemia, Despite treatment, the diabetic pregn ant women and those with daily hyperglycemia presented higher mean blood gl ucose levels compared to controls (76.6 +/- 10.2 mg/dl), The pregnancies co mplicated by diabetes and by daily hyperglycemia were characterized by a hi gh incidence of prematurity, macrosomia, large for gestational age newborn infants, malformation and fetal and neonatal death, with consequent perinat al mortality. The perinatal mortality of women with daily hyperglycemia was 10 times higher than that of the controls and was similar to that of the d iabetic patients. These adverse perinatal results emphasize the need for th e diagnosis and control of intrauterine hyperglycemia both in diabetic preg nant women and in women with an altered diurnal glycemic profile. Copyright (C) 2000 S. Karger AG, Basel.