Penaeidins, a family of antimicrobial peptides from penaeid shrimp (Crustacea, Decapoda)

Citation
D. Destoumieux et al., Penaeidins, a family of antimicrobial peptides from penaeid shrimp (Crustacea, Decapoda), CELL MOL L, 57(8-9), 2000, pp. 1260-1271
Citations number
78
Language
INGLESE
art.tipo
Review
Categorie Soggetti
Cell & Developmental Biology
Journal title
CELLULAR AND MOLECULAR LIFE SCIENCES
ISSN journal
1420-682X → ACNP
Volume
57
Issue
8-9
Year of publication
2000
Pages
1260 - 1271
Database
ISI
SICI code
1420-682X(200008)57:8-9<1260:PAFOAP>2.0.ZU;2-N
Abstract
The production of antimicrobial peptides represents a first-line host defen se mechanism of innate immunity that is widespread in nature. Only recently such effecters were isolated in crustacean species, whereas numerous antim icrobial peptides have been characterized from other arthropods, both insec ts and chelicerates. This review presents findings on a family of antimicro bial peptides, named penaeidins, isolated fi om the shrimp Penaeus vannamei . Their structure and antimicrobial properties as well as their immune func tion will be discussed through analyses of penaeidin gene expression and pe ptide distribution upon microbial challenge.