Surgery for pulmonary metastases from colorectal carcinoma

Citation
M. Inoue et al., Surgery for pulmonary metastases from colorectal carcinoma, ANN THORAC, 70(2), 2000, pp. 380-383
Citations number
19
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Cardiovascular & Respiratory Systems","Medical Research Diagnosis & Treatment
Journal title
ANNALS OF THORACIC SURGERY
ISSN journal
0003-4975 → ACNP
Volume
70
Issue
2
Year of publication
2000
Pages
380 - 383
Database
ISI
SICI code
0003-4975(200008)70:2<380:SFPMFC>2.0.ZU;2-E
Abstract
Background. This study aims to clarify which patients would benefit by surg ery for pulmonary metastases from colorectal carcinoma. Methods. A retrospective study was undertaken in 25 patients who had underg one complete resection. In all cases, prethoracotomy carcinoembryonic antig en (CEA) level was measured and mediastinal or hilar lymph nodes were histo logically examined. Results. Overall 5-year survival was 39.2%. The 5-year survival rate for pa tients with a normal CEA level was 61.1%, as compared with 19.0% for patien ts with an elevated CEA level (p = 0.0423). The 5-year survival rate for pa tients without a lymph node metastasis was 49.5%, as compared with 14.3% fo r patients with a lymph node metastasis (p = 0.0032). No lymph node metasta sis was a predictor of longer survival by univariate and multivariate analy ses. The primary site, disease-free interval, and number and size of the me tastasis were not significant prognostic factors. Conclusions. A resection for pulmonary metastasis from colorectal carcinoma is effective in patients with a normal CEA level and without a lymph node metastasis. (C) 2000 by The Society of Thoracic Surgeons.