Autoantibody screening in subacute cerebellar ataxia

Citation
R. Trivedi et al., Autoantibody screening in subacute cerebellar ataxia, LANCET, 356(9229), 2000, pp. 565-566
Citations number
5
Language
INGLESE
art.tipo
Article
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
Journal title
LANCET
ISSN journal
0140-6736 → ACNP
Volume
356
Issue
9229
Year of publication
2000
Pages
565 - 566
Database
ISI
SICI code
0140-6736(20000812)356:9229<565:ASISCA>2.0.ZU;2-B
Abstract
In a retrospective study of 280 sera from patients presenting with cerebell ar signs, seven of whom had proved positive for the typical paraneoplastic serum antibodies that were requested by the clinicians, raised concentratio ns of antibodies to voltage-gated calcium channels or to glutamic acid deca rboxylase were detected in a further seven sera. Systematic screening for t hese and other antibodies in future cases should help in the diagnosis and management of the patients.