New triterpenoid saponins from the sponge Melophlus isis

Citation
Hs. Lee et al., New triterpenoid saponins from the sponge Melophlus isis, J NAT PROD, 63(7), 2000, pp. 915-919
Citations number
18
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
0163-3864 → ACNP
Volume
63
Issue
7
Year of publication
2000
Pages
915 - 919
Database
ISI
SICI code
0163-3864(200007)63:7<915:NTSFTS>2.0.ZU;2-E
Abstract
Four new triterpenoid saponins were isolated, along with two known 30-norla nostane-type saponins-sarasinosides A(1) (1) and A(3) (2)-from the sponge M elophlus isis collected from Guam. The structures of these new compounds (3 -6) proved to be 30-norlanosta-8(14),24-dien-23-ones bearing two hydroxyl g roups or the corresponding methoxy groups at the 9 alpha,15 alpha- and 9 al pha,15 beta-positions and the pentasaccharide portion identical with those of 1 and 2 at the 3 beta position, by spectral, chemical, and GC analyses.