Study on highly sensitive potentiometric IgG immunosensor

Citation
Cl. Feng et al., Study on highly sensitive potentiometric IgG immunosensor, SENS ACTU-B, 66(1-3), 2000, pp. 190-192
Citations number
5
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences","Instrumentation & Measurement
Journal title
SENSORS AND ACTUATORS B-CHEMICAL
ISSN journal
0925-4005 → ACNP
Volume
66
Issue
1-3
Year of publication
2000
Pages
190 - 192
Database
ISI
SICI code
0925-4005(20000725)66:1-3<190:SOHSPI>2.0.ZU;2-1
Abstract
A novel potentiometric immunosensor for detection of immunogloblin G (IgG) has been developed by means of covalent immobilization of anti-immunoglobli n G on a silver (Ag) electrode. The detection is based on the change in the electric potential before and after the antigen-antibody reaction. Tests r elating to the detection of IgG demonstrate that the immunosensor exhibits a high level of sensitivity, stability and reproducibility, the linear resp onse range was 0.2-1.2 ng/ml for IgG solution and the lifetime was more tha n 28 days. (C) 2000 Elsevier Science S.A. All rights reserved.