Immunohistochemical study of lymphocyte populations infiltrating the gastric mucosa of beagle dogs experimentally infected with Helicobacter pylori

Citation
G. Rossi et al., Immunohistochemical study of lymphocyte populations infiltrating the gastric mucosa of beagle dogs experimentally infected with Helicobacter pylori, INFEC IMMUN, 68(8), 2000, pp. 4769-4772
Citations number
24
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Immunology
Journal title
INFECTION AND IMMUNITY
ISSN journal
0019-9567 → ACNP
Volume
68
Issue
8
Year of publication
2000
Pages
4769 - 4772
Database
ISI
SICI code
0019-9567(200008)68:8<4769:ISOLPI>2.0.ZU;2-P
Abstract
Experimental infection of beagle dogs with Helicobacter pylori induces recr uitment to the gastric mucosae of neutrophils at early stages and later of mononuclear cells that organize into lymphoid follicles. These structures b ecome macroscopically evident and consist of peripheral CD4(+) T lymphocyte s and central CD21(+) B lymphocytes. Furthermore, transient expression of i nterleukin-8 (IL-8) parallels the presence of neutrophils in the gastric mu cosae, whereas expression of IL-6 tends to persist chronically.