Aspiration and imprint cytopathology of thyroid carcinoma associated with familial adenomatous polyposis

Citation
Jm. Chong et al., Aspiration and imprint cytopathology of thyroid carcinoma associated with familial adenomatous polyposis, DIAGN CYTOP, 23(2), 2000, pp. 101-105
Citations number
12
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology
Journal title
DIAGNOSTIC CYTOPATHOLOGY
ISSN journal
8755-1039 → ACNP
Volume
23
Issue
2
Year of publication
2000
Pages
101 - 105
Database
ISI
SICI code
8755-1039(200008)23:2<101:AAICOT>2.0.ZU;2-A
Abstract
Thyroid carcinomas occur in association with familial adenomatous polyposis (FAP), and some are the first symptom of FAP. Although several histologica l features have been reported, the cytopathology of FAP-associated thyroid carcinoma has not yet been described. We report on two cases of FAP-associa ted thyroid carcinomas diagnosed by fine-needle aspiration biopsy and one c ase imprinted after resection. All 3 patients belonged to the same family, and thyroid carcinoma was the first symptom of the proband. Cytological fea tures include fascicular or whorl formation of spindle cells with papillary , follicular, and/or solid architectures, in addition to the typical featur es of papillary carcinoma. The cytological features of FAP-associated thyro id carcinomas are characteristic and may suggest FAP. Diagn. Cytopathol. 20 00;23:101-105. (C) 2000 Wiley-Liss, Inc.