Palladium-catalyzed diastereoselective cyclization of the allylic precursors. A concise synthetic route to 3-azabicyclo[3.3.0]octane and hydroisoindole skeletons

Citation
Yg. Suh et al., Palladium-catalyzed diastereoselective cyclization of the allylic precursors. A concise synthetic route to 3-azabicyclo[3.3.0]octane and hydroisoindole skeletons, SYN COMMUN, 30(16), 2000, pp. 3053-3060
Citations number
15
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNTHETIC COMMUNICATIONS
ISSN journal
0039-7911 → ACNP
Volume
30
Issue
16
Year of publication
2000
Pages
3053 - 3060
Database
ISI
SICI code
0039-7911(2000)30:16<3053:PDCOTA>2.0.ZU;2-V
Abstract
A useful variant of palladium-catalyzed 1,2-diastereoselective cyclization of the allylic precursors based on the steric nature of the anion stabilizi ng groups has been developed. The 1,1,2-trisubstituted cycloalkane products have also been efficiently transformed into the azabicyclic systems.