Sedative activity of two flavonol glycosides isolated from the flowers of Albizzia julibrissin Durazz

Citation
Th. Kang et al., Sedative activity of two flavonol glycosides isolated from the flowers of Albizzia julibrissin Durazz, J ETHNOPHAR, 71(1-2), 2000, pp. 321-323
Citations number
6
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Pharmacology & Toxicology
Journal title
JOURNAL OF ETHNOPHARMACOLOGY
ISSN journal
0378-8741 → ACNP
Volume
71
Issue
1-2
Year of publication
2000
Pages
321 - 323
Database
ISI
SICI code
0378-8741(200007)71:1-2<321:SAOTFG>2.0.ZU;2-R
Abstract
The flowers of Albizzia julibrissin are used as a sedative in oriental trad itional medicine. The phytochemical study of this plant allowed the isolati on of two flavonol glycosides, quercitrin (1) and isoquercitrin (2). The se dative activity of these compounds was evaluated, and both compounds 1 and 2 increased pentobarbital-induced sleeping time in dose-dependent manner in mice. These results support the use of the flowers of this plant as a seda tive agent. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.