Efficacy of influenza vaccine in the elderly: reduction in risks of mortality and morbidity during an influenza A (H3N2) epidemic for the elderly in nursing homes

Citation
Y. Deguchi et Y. Takasugi, Efficacy of influenza vaccine in the elderly: reduction in risks of mortality and morbidity during an influenza A (H3N2) epidemic for the elderly in nursing homes, INT J CL L, 30(1), 2000, pp. 1-4
Citations number
16
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Medical Research Diagnosis & Treatment
Journal title
INTERNATIONAL JOURNAL OF CLINICAL & LABORATORY RESEARCH
ISSN journal
0940-5437 → ACNP
Volume
30
Issue
1
Year of publication
2000
Pages
1 - 4
Database
ISI
SICI code
0940-5437(200003)30:1<1:EOIVIT>2.0.ZU;2-8
Abstract
The effect of influenza vaccination on the occurrence and severity of influ enza virus infection in elderly nursing home residents was studied during a n influenza A (H3N2) epidemic in Japan. Of 22,462 individuals living in 301 welfare nursing homes, 10,739 received inactivated (subunit) influenza vac cine. Through the period November 1998 to March 1999, there were 950 cases of influenza infection diagnosed clinically, with virus isolation and/or se rology. There were statistically significantly Fewer cases of influenza, ho spital admissions due to severe infection, and deaths due to influenza in t he vaccinated cohort compared with the unvaccinated controls. No serious ad verse reactions to vaccination were recorded. Thus influenza vaccination is safe: and effective in this population, and should be an integral part of the routine care of persons aged 65 years and over residing in nursing home s.