Lymphocytic adenohypophysitis mimicking a pituitary macroadenoma

Citation
C. Alexiadou-rudolf et al., Lymphocytic adenohypophysitis mimicking a pituitary macroadenoma, NEUROSURG R, 23(2), 2000, pp. 112-116
Citations number
20
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Neurology
Journal title
NEUROSURGICAL REVIEW
ISSN journal
0344-5607 → ACNP
Volume
23
Issue
2
Year of publication
2000
Pages
112 - 116
Database
ISI
SICI code
0344-5607(200006)23:2<112:LAMAPM>2.0.ZU;2-3
Abstract
A 24-year-old woman developed headache and rapidly progressive visual distu rbances during the last trimester of her first pregnancy. Magnetic resonanc e tomography (MRI) of the brain documented an intra- and suprasellar mass l esion. For preservation of vision, transsphenoidal microsurgical decompress ion was performed. Immediately postoperatively, visual acuity improved and hemianopia resolved. Histological examination yielded the diagnosis of prim ary lymphocytic adenohypophysitis. This is a rare inflammatory pituitary di sease. There are no typical clinical, laboratory, or radiological findings that allow precise preoperative diagnosis. Even though this autoimmune diso rder is principally steroid-responsive, an improvement of visual disturbanc es under steroid therapy cannot be predicted, Therefore, surgery is justifi ed not only to establish the diagnosis, but also to restore vision by decom pression of the optic nerves and the chiasm.