Pediatric mastocytosis

Citation
K. Hartmann et Dd. Metcalfe, Pediatric mastocytosis, HEMAT ONCOL, 14(3), 2000, pp. 625
Citations number
70
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Hematology,"Cardiovascular & Hematology Research
Journal title
HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA
ISSN journal
0889-8588 → ACNP
Volume
14
Issue
3
Year of publication
2000
Database
ISI
SICI code
0889-8588(200006)14:3<625:PM>2.0.ZU;2-T
Abstract
Mastocytosis is a rare disorder characterized by accumulation of mast cells in tissues. Sixty-five percent of patients with mastocytosis are children. Whereas mastocytosis in adults is usually persistent or progressive, pedia tric mastocytosis is often transient and limited. Recent studies suggest th at childhood-onset and adult-onset mastocytosis also differ in their pathog enesis. This article reviews the various forms of pediatric mastocytosis wi th a special focus on new pathogenetic findings.