Bulk acoustic wave sensing technique applied to dibazol assay in serum andurine

Citation
Ym. Long et al., Bulk acoustic wave sensing technique applied to dibazol assay in serum andurine, ANAL SCI, 16(6), 2000, pp. 615-619
Citations number
21
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
ANALYTICAL SCIENCES
ISSN journal
0910-6340 → ACNP
Volume
16
Issue
6
Year of publication
2000
Pages
615 - 619
Database
ISI
SICI code
0910-6340(200006)16:6<615:BAWSTA>2.0.ZU;2-Z
Abstract
A simple, rapid, specific and sensitive method for the assay of dibazol usi ng a bulk acoustic wave technique is described. PVC film containing Various activants was coated on one electrode of a piezoelectric quartz crystal to fabricate a dibazol bulk acoustic wave (BAW) sensor for the assay of dibaz ol. Neither a sample pretreatment nor separation was required. The logarith m of the frequency shift of the dibazol BAW sensor shows a linear relations hip to the logarithm of the concentration of dibazol over the range 4.0x10( -8) - 9.0x10(-4) M with a detection limit of 4.0x10-8 M. In this work, thre e kinds of ion-pair complexes, namely, dibazol with dicyclohexylnaphthalene sulfonate (DDCHNS), diisobutylnaphthalene sulfonate (DDBNS) and tetrapheny lborate (DTPB), were synthesized and investigated. The influencing factors were also examined and optimized. A comparison of the BAW sensing technique with other methods for assaying dibazol was made.