We have applied bacteriophage display technology to construct and analyze t
he diversity of an IgG library of >1 x 10(8) clones from an adult sheep imm
unized against the hapten atrazine. We have identified eight new V-H gene f
amilies (V(H)2-V(H)9) and five new V kappa gene families (V kappa V-V kappa
IX). The heavy and kappa light chain variable region gene loci were found
to be far more diverse than previously thought.