Endothelial dysfunction in arterial hypertension

Citation
F. Contreras et al., Endothelial dysfunction in arterial hypertension, J HUM HYPER, 14, 2000, pp. S20-S25
Citations number
36
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Cardiovascular & Respiratory Systems
Journal title
JOURNAL OF HUMAN HYPERTENSION
ISSN journal
0950-9240 → ACNP
Volume
14
Year of publication
2000
Supplement
1
Pages
S20 - S25
Database
ISI
SICI code
0950-9240(200004)14:<S20:EDIAH>2.0.ZU;2-7
Abstract
Systemic arterial pressure is a dynamic and reactive physiological paramete r depending on a great many factors. The endothelial cells of the vascular system are responsible for many biochemical reactions maintaining vascular homeostasis and therefore arterial pressure. Arterial hypertension, atheros clerosis and endothelial dysfunction constitute risk factors increasing mor bidity and mortality of cardiovascular origin. These three elements are clo sely related and frequently act simultaneously damaging different organs. I n this paper we review the physiology of the endothelium and the probable c onsequences of endothelial dysfunction on the pathophysiology of arterial p ressure.