The electrophilic amination of carbanions: An unconventional new entry to C-N bond formation

Citation
P. Dembech et al., The electrophilic amination of carbanions: An unconventional new entry to C-N bond formation, CHEM-EUR J, 6(8), 2000, pp. 1281-1286
Citations number
34
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Chemistry
Journal title
CHEMISTRY-A EUROPEAN JOURNAL
ISSN journal
0947-6539 → ACNP
Volume
6
Issue
8
Year of publication
2000
Pages
1281 - 1286
Database
ISI
SICI code
0947-6539(20000414)6:8<1281:TEAOCA>2.0.ZU;2-7
Abstract
The electrophilic amination of carbanions allows the preparation of a wide range of amines through an unconventional C-N bond-forming reaction. The co ncepts behind the varied synthetic approaches, classified by the nature of the aminating agent and of the organometallic species, are discussed. The m ild operational conditions, the high selectivity, and the availability of t he starting materials are good assets of these processes which nicely compl ement each other, New appealing and flexible routes can be devised, leading in several cases to the synthesis of otherwise not easily accessible N-con taining compounds.