Fine-needle aspiration cytology of a case of oncocytic adrenocortical carcinoma

Citation
S. Krishnamurthy et al., Fine-needle aspiration cytology of a case of oncocytic adrenocortical carcinoma, DIAGN CYTOP, 22(5), 2000, pp. 299-303
Citations number
15
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology
Journal title
DIAGNOSTIC CYTOPATHOLOGY
ISSN journal
8755-1039 → ACNP
Volume
22
Issue
5
Year of publication
2000
Pages
299 - 303
Database
ISI
SICI code
8755-1039(200005)22:5<299:FACOAC>2.0.ZU;2-B
Abstract
We report on the results of fine-needle aspiration cytology of a case of on cocytic adrenocortical carcinoma in a 39-yr-old man. The tumor invaded the inferior vena cava and extended rip to the right atrium. Aspirate smears we re very cellular and showed a monomorphic population of large polyhedral ce lls with abundant granular cytoplasm, predominantly distributed singly. Mit otic activity was inconspicuous, and there was no necrosis. Immunohistochem ically, the tumor cells were positive for vimentin, cytokeratin, and p53, a nd negative for synaptophysin, chromogranin, inhibin, and S-100. Ultrastruc turally, the cytoplasm of the tumor cells was packed with mitochondria. The patient underwent left radical nephrectomy as well as a combined cardiopul monary bypass, with atriotomy and resection of the tumor from the right atr ium and inferior vena cava. Three months of postoperative follow-rip were u neventful. Diagn. Cytopathol. 2000;22:299-303. (C) 2000 Wiley-Liss, Inc.