Cancer of the tongue in patients less than forty

Citation
Kt. Pitman et al., Cancer of the tongue in patients less than forty, HEAD NECK, 22(3), 2000, pp. 297-302
Citations number
31
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Otolaryngology
Journal title
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
ISSN journal
1043-3074 → ACNP
Volume
22
Issue
3
Year of publication
2000
Pages
297 - 302
Database
ISI
SICI code
1043-3074(200005)22:3<297:COTTIP>2.0.ZU;2-U
Abstract
Introduction. It is the opinion of many surgeons that the biologic potentia l of cancer that develops in young people is different compared with older patients. Prior reports on small series of patients addressing this issue h ave inadequate statistical power to resolve the question. Methods. By use of the techniques of meta-analysis, patients less than 40 y ears old who had undergone treatment of squamous cell carcinoma (SCC) of th e oral tongue were examined. Twenty-eight patients who were encountered in the Department of Otolaryngology, University of Pittsburgh School of Medici ne, and 94 patients were identified in the literature for a total of 122 pa tients <40 years old. A control group of 150 patients, aged 40 years and ol der treated for SCC of the oral tongue between 1982 and 1994 was identified . Results. Three-year disease-free survival in the group of patients aged les s than 40 was 53.3% compared with 3-year disease free survivorship of 55.0% in the older cohort of patients. Conclusion. These data strongly suggest that the outcomes of treatment for SCC of the oral tongue in young patients are similar compared with patients older than 40 with similar extent of disease. (C) 2000 John Wiley & Sons, Inc.