Schnitzler syndrome: A case study

Citation
G. Sanchez et al., Schnitzler syndrome: A case study, J INVES ALL, 10(1), 2000, pp. 41-43
Citations number
9
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Clinical Immunolgy & Infectious Disease
Journal title
JOURNAL OF INVESTIGATIONAL ALLERGOLOGY & CLINICAL IMMUNOLOGY
ISSN journal
1018-9068 → ACNP
Volume
10
Issue
1
Year of publication
2000
Pages
41 - 43
Database
ISI
SICI code
1018-9068(200001/02)10:1<41:SSACS>2.0.ZU;2-A
Abstract
Schnitzler syndrome is a clinical entity of unknown etiopathogenesis and is an unusual cause of chronic urticaria. It is characterized by the presenta tion of a monoclonal band, especially IgM, as well as fever, asthenia and a rthralgia. We present the case of a 48-year-old man with 5 years of recurre nt urticarial lesions, slight itching, as well as lip, face and occasional pharyngeal edema. The patient had also suffered from fever and right hip an d left knee arthralgia. The protein electrophoresis and the immunoelectroph oresis presented an IgG band and a slight lambda band, which is suggestive of a monoclonal gammopathy. The bone marrow examination showed a slight inc rease in the lymphoplasmatic cells. The marrow biopsy was negative. in orde r to rule out tumorous, infectious and rheumatic processes as well as colla gen diseases, other complementary examinations were performed with negative results. The diagnosis of Schnitzler syndrome as a cause of chronic urtica ria requires a thorough study in order to rule out other systemic processes provoking the same symptoms.