Antimicrobial susceptibility and frequency of occurrence of clinical bloodisolates in Europe from the SENTRY Antimicrobial Surveillance Program, 1997 and 1998

Citation
Ac. Fluit et al., Antimicrobial susceptibility and frequency of occurrence of clinical bloodisolates in Europe from the SENTRY Antimicrobial Surveillance Program, 1997 and 1998, CLIN INF D, 30(3), 2000, pp. 454-460
Citations number
32
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Immunology
Journal title
CLINICAL INFECTIOUS DISEASES
ISSN journal
1058-4838 → ACNP
Volume
30
Issue
3
Year of publication
2000
Pages
454 - 460
Database
ISI
SICI code
1058-4838(200003)30:3<454:ASAFOO>2.0.ZU;2-3
Abstract
As part of the European arm of the SENTRY Antimicrobial Surveillance Progra m, 25 European university hospitals referred 9613 blood isolates for in vit ro testing against >20 antimicrobial agents. Escherichia coli, Staphylococc us aureus, coagulase-negative Staphylococcus, Pseudomonas aeruginosa, and K lebsiella pneumoniae were the 5 most frequent isolates and accounted for tw o-thirds of all referrals, with minor regional variation. Of these, similar to 0.36% of E. coli and 16.7% of K, pneumoniae isolates proved to be poten tial extended-spectrum beta-lactamase producers, and their incidence clearl y varied regionally Quinolone resistance was detected among gram-negative s pecies; in particular, P. aeruginosa and Acinetobacter species. Considerabl e regional variation was observed in the incidences of methicillin resistan ce in S. aureus and penicillin resistance in Streptococcus pneumoniae. The incidence of vancomycin resistance in enterococci was relatively low overal l and primarily associated with Enterococcus faecium. However, extrapolatio n of these data to smaller and nonteaching hospitals should be undertaken w ith caution, since resistance rates may be lower in these facilities.