Directional coronary atherectomy in intermediate sized vessels: Final results of the intermediate vessel atherectomy trial (IVAT)

Citation
L. Cannon et al., Directional coronary atherectomy in intermediate sized vessels: Final results of the intermediate vessel atherectomy trial (IVAT), CATHET C IN, 49(4), 2000, pp. 396-400
Citations number
22
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Cardiovascular & Respiratory Systems
Journal title
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
ISSN journal
1522-1946 → ACNP
Volume
49
Issue
4
Year of publication
2000
Pages
396 - 400
Database
ISI
SICI code
1522-1946(200004)49:4<396:DCAIIS>2.0.ZU;2-H
Abstract
Revascularization options for intermediate sized vessels (2.5-2.9 mm) have historically been limited. IVAT is a pilot study to assess the efficacy and safety of debulking intermediate sized vessels using directional coronary atherectomy (DCA). Between March 1996 and June 1997, 50 patients were enrol led at seven hospitals in the United States. Of those patients, 70% present ed with unstable angina and 52% had single vessel disease. Of the lesions t reated, 96% were de novo. Adjunctive PTCA after DCA was performed in 90% of cases at the discretion of the investigator to maximize luminal diameter. The GTO DCA device was used in 90% of cases. Procedural success (residual s tenosis <50% without major complications) was 94%. Stents were placed in 12 % of patients. The only complications were three non-Q wave Mis. Mean refer ence vessel diameter increased from 2.49 mm pre-procedure to 2.57 mm after DCA and 2.61 post-procedure; mean MLD increased from 0.76 mm to 2.03 mm to 2.31 mm; and mean stenosis decreased from 70% to 21% post DCA and to 11% po st procedure, At six months follow-up, 18.0% of target lesions required rev ascularization. fetal revascularization, including non-target vessels, was 32%, These results suggest that DCA has a high procedural success rate and a low target lesion revascularization rate in intermediate sized vessels. ( C) 2000 Wiley-Liss, Inc.