An expedient synthesis of novel [1,2,4]triazolo[3,2-d] [1,5]benzothiazepine] derivatives

Citation
Xj. Liu et al., An expedient synthesis of novel [1,2,4]triazolo[3,2-d] [1,5]benzothiazepine] derivatives, SYNTHESIS-S, (3), 2000, pp. 435-441
Citations number
34
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
SYNTHESIS-STUTTGART
ISSN journal
0039-7881 → ACNP
Issue
3
Year of publication
2000
Pages
435 - 441
Database
ISI
SICI code
0039-7881(200003):3<435:AESON[>2.0.ZU;2-X
Abstract
The synthesis of a series of unprecedented tricyclic heterocycles, 1,2,4-tr iazolo[3,2-d][1,5]benzothiazepine 6-oxides (5a-i), was accomplished via cyc loaddition of the allene-like cations 3, derived from thiochroman-4-one ary lhydrazones, to the triple bond of nitriles and ensuing rings expansion ann ulation. The structure of one product (5h) has been unambiguously determine d by X-ray diffraction analysis.