Topical application of capsaicin for the treatment of localized pain in the temporomandibular joint area

Citation
E. Winocur et al., Topical application of capsaicin for the treatment of localized pain in the temporomandibular joint area, J OROFAC P, 14(1), 2000, pp. 31-36
Citations number
27
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Dentistry/Oral Surgery & Medicine
Journal title
JOURNAL OF OROFACIAL PAIN
ISSN journal
1064-6655 → ACNP
Volume
14
Issue
1
Year of publication
2000
Pages
31 - 36
Database
ISI
SICI code
1064-6655(200024)14:1<31:TAOCFT>2.0.ZU;2-R
Abstract
Aims: To determine the effectiveness of topical capsaicin cream application on localized pain in the temporomandibular joint (TMJ) area. Methods: A ra ndomized, double-blind, placebo-controlled study was conducted on 30 patien ts suffering from unilateral pain in the TMJ area. Patients were randomly d ivided into experimental and placebo groups; they were instructed to apply 0.025% capsaicin cream or its vehicle to the painful TMJ area 4 times daily for 4 weeks. Subjective parameters of present pain, most severe pain, effe ct of pain on daily activities, and pain relief were assessed each week on a visual analog scale. Muscle and joint sensitivity to palpation on the pai nful and contralateral joints and maximal mouth opening (assisted/passive a nd non-assisted/active) were examined weekly by the same experienced examin er. Results: Capsaicin cream produced no statistically significant influenc e on measured variables when compared to placebo. Both experimental and pla cebo groups showed statistically significant improvement in most variables during the experiment. Conclusion: The factor of time had a major effect in the non-specific improvement of the parameters assessed. The placebo effec t played an important role in the treatment of patients with pain in the TM J area.