Effects of varying approaches for identifying respiratory disturbances on sleep apnea assessment

Citation
S. Redline et al., Effects of varying approaches for identifying respiratory disturbances on sleep apnea assessment, AM J R CRIT, 161(2), 2000, pp. 369-374
Citations number
15
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Cardiovascular & Respiratory Systems","da verificare
Journal title
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
ISSN journal
1073-449X → ACNP
Volume
161
Issue
2
Year of publication
2000
Pages
369 - 374
Database
ISI
SICI code
1073-449X(200002)161:2<369:EOVAFI>2.0.ZU;2-A
Abstract
Varying approaches to measuring the respiratory disturbance index (RDI) may lead to discrepant estimates of the severity of sleep-disordered breathing (SDB). In this study, we assessed the impact of varying the use of corrobo rative data (presence and degree of desaturation and/or arousal) to identif y hypopneas and apneas. The relationships among 10 RDIs defined by various definitions of apneas and hypopneas were assessed in 5,046 participants in the Sleep Heart Health Study (SHHS) who underwent overnight unattended 12-c hannel polysomnography (PSC). The magnitude of the median RDI varied 10-fol d (i.e., 29.3 when the RDI was based on events identified on the basis of f low or volume amplitude criteria alone to 2.0 for an RDI that required an a ssociated 5% desaturation with events). The correlation between RDIs based on different definitions ranged from 0.99 to 0.68. The highest correlations were among RDIs that required apneas and hypopneas to be associated with s ome level of desaturation. Lower correlations were observed between RDIs th at required desaturation as compared with RDIs defined on the basis of ampl itude criteria alone or associated arousal. These data suggest that differe nt approaches for measuring the RDI may contribute to substantial variabili ty in identification and classification of the disorder.