Stereoselective synthesis of 5-monoalkyl and 5,5-dialkylsubstituted noviose derivatives

Citation
Am. Periers et al., Stereoselective synthesis of 5-monoalkyl and 5,5-dialkylsubstituted noviose derivatives, TETRAHEDR L, 41(6), 2000, pp. 867-871
Citations number
23
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
0040-4039 → ACNP
Volume
41
Issue
6
Year of publication
2000
Pages
867 - 871
Database
ISI
SICI code
0040-4039(20000205)41:6<867:SSO5A5>2.0.ZU;2-2
Abstract
fThe stereoselective synthesis of 5-monosubstituted and 5,5-dialkylsubstitu ted noviose derivatives has been achieved starting from L-arabinose. These noviose derivatives could be used as useful building blocks in probing stru cture-activity relationships (SAR) of coumarin antibiotics that are inhibit ors of DNA gyrase. (C) 2000 Elsevier Science Ltd. All rights reserved.