Primary neuroendocrine small cell carcinoma of the breast

Citation
B. Samli et al., Primary neuroendocrine small cell carcinoma of the breast, ARCH PATH L, 124(2), 2000, pp. 296-298
Citations number
11
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology","Medical Research Diagnosis & Treatment
Journal title
ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE
ISSN journal
0003-9985 → ACNP
Volume
124
Issue
2
Year of publication
2000
Pages
296 - 298
Database
ISI
SICI code
0003-9985(200002)124:2<296:PNSCCO>2.0.ZU;2-3
Abstract
A 60-year-old Turkish woman presented with a left breast mass, which was co nsidered for neoadjuvant chemotherapy. By the end of the treatment cycles, the tumor had decreased in size, and the patient underwent modified radical mastectomy with axillary lymph node dissection. Pathologic examination of the tumor revealed a small cell carcinoma with neuroendocrine features conf irmed by immunohistochemical stains. Multiple axillary lymph nodes were inv olved by metastatic small cell carcinoma carrying the same morphologic char acteristics noted in the primary breast tumor. We hereby present this case as a primary neuroendocrine small cell carcinoma of the breast. This entity occurs very rarely in the breast, and fewer than a dozen cases have been r eported in the literature. Extrapulmonary small cell carcinoma of the breas t is reportedly a very aggressive tumor for which no consensus for treatmen t has yet been drawn.