Medications to treat alcoholism

Citation
Ba. Johnson et N. Ait-daoud, Medications to treat alcoholism, ALCOHOL R H, 23(2), 1999, pp. 99-106
Citations number
54
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Public Health & Health Care Science
Journal title
ALCOHOL RESEARCH & HEALTH
ISSN journal
1535-7414 → ACNP
Volume
23
Issue
2
Year of publication
1999
Pages
99 - 106
Database
ISI
SICI code
Abstract
Advances in neurobiology support the development of medications to treat al coholism by modifying the activity of specific chemical messengers (i.e., n eurotransmitters) in the brain. Among the most promising new medications is acamprosate, which appears to decrease the intensity of craving after a pe rson has stopped drinking. Naltrexone (ReVia(TM)) has been shown to decreas e alcohol consumption, although its practical effectiveness may be compromi sed by poor patient compliance and other factors. Ondansetron shows promise for decreasing drinking and increasing abstinence rates among early onset alcoholics, who respond poorly to psychosocial treatment alone. Researchers are investigating whether the use of specific medications in combination c an further enhance their effectiveness. Additional research is needed to de termine how medications interact with different psychosocial factors and tr eatments.