ACTIVE NUCLEAR TRANSPORT OF CHICKEN LIPOVITELLIN-2

Citation
A. Luo Zj",annikkalinnalakankkunen,"itkonen et Ph. Maenpaa, ACTIVE NUCLEAR TRANSPORT OF CHICKEN LIPOVITELLIN-2, Biochemical and biophysical research communications, 234(3), 1997, pp. 760-763
Citations number
17
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Biology,Biophysics
ISSN journal
0006-291X
Volume
234
Issue
3
Year of publication
1997
Pages
760 - 763
Database
ISI
SICI code
0006-291X(1997)234:3<760:ANTOCL>2.0.ZU;2-W
Abstract
Chicken lipovitellin-2 is a small, approximately 30 kDa yolk protein, derived from the intracellular breakdown of the precursor protein vite llogenin. In principle, lipovitellin-2 is small enough to directly dif fuse into the nucleus. Our results, however, demonstrate that its nucl ear transport is an active process which can be inhibited by wheat ger m agglutinin, chilling, and energy depletion. The N-terminal sequence analysis identifies chicken lipovitellin-2 beginning at Ala1544 in the C-terminal region of vitellogenin yielding of protein of 30,982 Da. ( C) 1997 Academic Press.