Tuberculous manifestations in the musculoskeletal system, exemplified by Poncet's disease

Citation
M. Kowalski et M. Seitz, Tuberculous manifestations in the musculoskeletal system, exemplified by Poncet's disease, SCHW MED WO, 129(47), 1999, pp. 1839-1842
Citations number
13
Language
TEDESCO
art.tipo
Article
Categorie Soggetti
General & Internal Medicine
Journal title
SCHWEIZERISCHE MEDIZINISCHE WOCHENSCHRIFT
ISSN journal
0036-7672 → ACNP
Volume
129
Issue
47
Year of publication
1999
Pages
1839 - 1842
Database
ISI
SICI code
0036-7672(19991127)129:47<1839:TMITMS>2.0.ZU;2-F
Abstract
Tuberculosis is a communicable disease that is occasionally complicated by arthritis, either as part of a disseminated primary infection or through la te reactivation, often in immunocompromised hosts such as elderly people, H IV-positive patients or patients under immunosuppressive therapy. Even thou gh musculoskeletal manifestations occur in only about 2% of tuberculosis ca ses, they can be very heterogeneous and present as spondylitis, osteomyelit is or mono-oligo-polyarthritis. Because of the potential for disastrous out comes in cases where the diagnosis is delayed, it is important to recognise the multiple rheumatological manifestations of tuberculosis. This case rep ort on a patient with Poncet's disease discusses a current hypothesis regar ding pathogenesis of reactive arthritis based on rheumatological manifestat ions of tuberculosis. The genomic detection of Mycobacterium tuberculosis, to differentiate between infectious arthritis and reactive arthritis by pol ymerase chain reaction, is of particular importance.