Audiologic evaluation of neonates with severe hyperbilirubinemia using transiently evoked otoacoustic emissions and auditory brainstem responses

Citation
Ck. Rhee et al., Audiologic evaluation of neonates with severe hyperbilirubinemia using transiently evoked otoacoustic emissions and auditory brainstem responses, LARYNGOSCOP, 109(12), 1999, pp. 2005-2008
Citations number
25
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Otolaryngology
Journal title
LARYNGOSCOPE
ISSN journal
0023-852X → ACNP
Volume
109
Issue
12
Year of publication
1999
Pages
2005 - 2008
Database
ISI
SICI code
0023-852X(199912)109:12<2005:AEONWS>2.0.ZU;2-Y
Abstract
Objectives: To audiologically clarify the lesion site and to test the relia bility of transiently evoked otoacoustic emissions (TEOAEs) in hearing scre ening of hyperbilirubinemic neonates. Study Design: Eleven neonates with se vere hyperbilirubinemia who had exchange transfusion in the neonatal intens ive care unit of an academic hospital over a 3-year period were included in this study. They were tested with auditory brainstem response (ABR) and TE OAEs after exchange transfusion during hospitalization or at an immediate f ollow-up visit after discharge. Follow-up ABR tests were performed when inf ants showed significant hearing loss. Methods: ABR and TEOAE tests were per formed on the 11 neonates with severe hyperbilirubinemia after exchange tra nsfusion. Follow-up ABR tests were carried out in 3-month intervals in the four neonates who showed abnormal or no response on initial ABR. Results: F our neonates showed abnormal or no response and the other seven demonstrate d normal response in ABR. All 11 neonates passed TEOAEs. Two neonates showe d improvement in auditory function at 3- or 6-month follow-up ABR. Conclusi on: The results of this study indicate that the site of lesion in hearing l oss caused by hyperbilirubinemia may be at the retrocochlear location while the cochlea remains intact. TEOAEs may have limitations in evaluation of h earing in the neonates with hyperbilirubinemia.