Value of Ga-67SPECT in monitoring the effects of therapy in invasive aspergillosis of the sphenoid sinus

Citation
Ky. Tzen et al., Value of Ga-67SPECT in monitoring the effects of therapy in invasive aspergillosis of the sphenoid sinus, CLIN NUCL M, 24(12), 1999, pp. 938-941
Citations number
28
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Radiology ,Nuclear Medicine & Imaging
Journal title
CLINICAL NUCLEAR MEDICINE
ISSN journal
0363-9762 → ACNP
Volume
24
Issue
12
Year of publication
1999
Pages
938 - 941
Database
ISI
SICI code
0363-9762(199912)24:12<938:VOGIMT>2.0.ZU;2-Q
Abstract
Purpose: We report a case of invasive sphenoid sinus aspergillosis clinical ly presenting as a pituitary mass. Methods: After exploration via the trans-sphenoidal approach and subsequent treatment with amphotericin-B, Ga-67 brain SPECT was performed twice to mo nitor the therapeutic effect. Results: Three months after antifungal treatment, Ga-67 brain SPECT showed partial resolution of the lesion in the sella turcica region. The patient c ontinued with fluconazole treatment for another 2 months and received anoth er Ga-67 brain SPECT, which showed complete clearing of the previous lesion . Conclusion: Ga-67 brain SPECT may play a potentially useful role in monitor ing the therapeutic effect of treatment of invasive sphenoid sinus aspergil losis.