Kainate receptor pharmacology and physiology

Authors
Citation
D. Bleakman, Kainate receptor pharmacology and physiology, CELL MOL L, 56(7-8), 1999, pp. 558-566
Citations number
109
Language
INGLESE
art.tipo
Review
Categorie Soggetti
Cell & Developmental Biology
Journal title
CELLULAR AND MOLECULAR LIFE SCIENCES
ISSN journal
1420-682X → ACNP
Volume
56
Issue
7-8
Year of publication
1999
Pages
558 - 566
Database
ISI
SICI code
1420-682X(19991115)56:7-8<558:KRPAP>2.0.ZU;2-H
Abstract
Glutamate is the primary neurotransmitter in the central nervous system. On e of the classes of ionotropic glutamate receptors is kainate receptors. Re cent developments in the pharmacology of kainate receptors have resulted in the emergence of several selective agonists and antagonists. These compoun ds have allowed scientists to begin to probe the functional properties of t hese receptors in neurons and gain a better understanding of the role of th ese receptors in the nervous system.