To identify lung and head-and-neck cancer patients who will have difficulty
stopping smoking it is necessary to measure the severity of their nicotine
dependence. In this study, we compiled a Japanese version of the Fagerstro
m test for nicotine dependence (FTND) and examined its reliability and vali
dity. One hundred and fifty-one cancer patients participated in this study
and took our Japanese version of the FTND, Socio-demographic and medical da
ta and information about smoking habits were obtained from a semi-structure
d interview, and the patients' nicotine dependence was evaluated according
to the Diagnostic and Statistical Manual of Mental Disorders, 3rd Ed., Rev.
(DSM-III-R). The mean FTND scores+/-SD of the group with nicotine dependen
ce and the group without nicotine dependence were 6.85+/-2.00 and 3.70+/-2.
13 respectively, and the difference was significant (P<0.001, Mann-Whitney'
s U-test), The test-retest correlation was 0.75, Cronbach's a of the FTND w
as 0.66, The FTND score correlated significantly with the number of satisfi
ed criteria of nicotine dependence (r=0.70; P<0.001,, Pearson's correlation
), By using a receiver-operating-characteristic curve, we determined a scor
e of 5/6 as a suitable cut-off point for nicotine dependence; this point ga
ve high sensitivity and specificity (0.75 and 0.80, respectively). These re
sults suggest that our Japanese version of FTND is a reliable and valid mea
sure of nicotine dependence in patients with smoking-related cancers.