Gibberellin signal transduction presents ... the SPY who O-GlcNAc'd me

Citation
Tm. Thornton et al., Gibberellin signal transduction presents ... the SPY who O-GlcNAc'd me, TRENDS PL S, 4(11), 1999, pp. 424-428
Citations number
41
Language
INGLESE
art.tipo
Review
Categorie Soggetti
Plant Sciences","Animal & Plant Sciences
Journal title
TRENDS IN PLANT SCIENCE
ISSN journal
1360-1385 → ACNP
Volume
4
Issue
11
Year of publication
1999
Pages
424 - 428
Database
ISI
SICI code
1360-1385(199911)4:11<424:GSTP.T>2.0.ZU;2-V
Abstract
Although the molecular mechanisms by which plants respond to gibberellins a re largely unknown, several components of the signal transduction pathway h ave been identified and a broad outline of how these components act in sign al transduction is emerging. One component of the pathway, SPINDLY, is beli eved to be an O-GlcNAc transferase that post-translationally modifies cytos olic and nuclear proteins by the addition of O-linked N-acetylglucosamine. Although analysis of the properties of O-GlcNAc-modified proteins from anim als has led to the hypothesis that this modification is regulatory, it has not been linked to specific signal transduction pathways.