Recovery of olfactory function after an anterior craniofacial approach

Citation
K. Saito et al., Recovery of olfactory function after an anterior craniofacial approach, SKULL BAS S, 9(3), 1999, pp. 201-206
Citations number
11
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Neurology
Journal title
SKULL BASE SURGERY
ISSN journal
1052-1453 → ACNP
Volume
9
Issue
3
Year of publication
1999
Pages
201 - 206
Database
ISI
SICI code
1052-1453(1999)9:3<201:ROOFAA>2.0.ZU;2-8
Abstract
We assessed recovery of olfactory function in five consecutive patients who underwent surgical resection of midline skull base tumors using an anterio r craniofacial approach in which the cribriform plate was mobilized with th e dura. Olfactory function was evaluated before and after surgery using an intravenous olfactory test with prosultiamine and also a standard olfactory acuity test; Before surgery, one patient showed anosmia attributable tp ob struction of the nasal cavity and olfactory cleft, and four patients showed normal olfactory function. After surgery, one patient was irreversibly ano smic, probably because Of intradural dissection of the olfactory tracts. Th e other four patients, including the patient showing anosmia preoperatively , reported subjective recovery of olfaction 3 to 8 weeks after surgery. Int ravenous and standard olfactory acuity tests indicated recovery of olfactio n to the normal range in three patients and decreased olfactory function in one. With careful preservation of the olfactory system and of the integrit y of the nasal cavity, olfactory function was found to recover after skull base resections via the anterior craniofacial approach.