Usefulness of clinical scores to predict outcome in bacterial meningitis

Citation
S. Merkelbach et al., Usefulness of clinical scores to predict outcome in bacterial meningitis, INFECTION, 27(4-5), 1999, pp. 239-243
Citations number
32
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Immunology
Journal title
INFECTION
ISSN journal
0300-8126 → ACNP
Volume
27
Issue
4-5
Year of publication
1999
Pages
239 - 243
Database
ISI
SICI code
0300-8126(1999)27:4-5<239:UOCSTP>2.0.ZU;2-L
Abstract
The predictive usefulness of clinical scores in patients with acute bacteri al meningitis was investigated, Fifty-one consecutive patients with acute b acterial meningitis were scored on days 1, 3, 5, 8, and 14 after admission according to the Sandinavian Stroke Scale (SSS), Glasgow Coma-Scale (GCS) a nd Hunt & Hess Scale (HH). As an index of their usefulness to predict the o utcome, the scales were correlated with short-term outcome on day 21 assess ed by the Glasgow Outcome Scale (GOS). The scores of a II th ree sea les co rrelated highly significantly with short-term outcome. Depending on the day of assessment, Spearman correlation coefficients ranged between 0.52 and 0 .88 for SSS, between 0.50 and 0.84 for CCS, and between -0.47 and -0.82 for HH. The scales differed in their ability to predict outcome on and after d ay 1: mortality was best predicted by GCS, and complete recovery was best p redicted by SSS. The use of sea les in bacterial meningitis provides a rati onal quantitative basis to predict outcome more graduated than in dead or a live. Because the sea les accentuate different aspects of outcome (e.g. mo rtality, restitution), the selection of a scale to be used in clinical tria ls should take into consideration the main focus of the study.