Alternative molecular imprinting, a facile way to introduce chiral recognition sites

Yoshikawa, M Izumi, J Kitao, T

M. Yoshikawa et al., Alternative molecular imprinting, a facile way to introduce chiral recognition sites, REACT FUNCT, 42(1), 1999, pp. 93-102

44

INGLESE

Article

Organic Chemistry/Polymer Science

REACTIVE & FUNCTIONAL POLYMERS

1381-5148 → ACNP

42

1

1999

93 - 102

ISI

1381-5148(19990915)42:1<93:AMIAFW>2.0.ZU;2-N

In the present article it is demonstrated that the alternative molecular im printimg technique is a facile one to introduce the chiral recognition site into polymeric membranes. In this technique, the 'molecular memory' of the print molecule, which is recognized or separated, is introduced into the m embrane at the same time as the polymeric membrane is being formed from its polymer solution. The molecularly imprinted polymeric membranes thus obtai ned exclusively recognize the print molecule family, which has the same abs olute configuration as the print molecule does. Enantioselective permeation can be attained by applying the optimum driving force for membrane transpo rt. Electrodialysis is a suitable method to supply such an optimum driving force. The alternative molecular imprinting technique is a facile technique to introduce a chiral recognition site into polymeric materials. (C) 1999 Elsevier Science B.V. All rights reserved.