Gallidermin production by Staphylococcus gallinarum was optimal using a new
developed medium consisting of 50 g yeast extract l(-1), 45 g CaCl2 l(-1)
and 5 g maltose l(-1). Medium optimisation led to the cost of the medium de
creasing by 93% compared to the previously used medium and in addition gain
ed a higher product yield. A scale-up of the process based on the new mediu
m was successfully tested up to a working volume of 200 l.