Chiral separations by open tubular capillary electrokinetic chromatography

Citation
Jj. Pesek et al., Chiral separations by open tubular capillary electrokinetic chromatography, J CHROMAT A, 853(1-2), 1999, pp. 151-158
Citations number
17
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Chemistry & Analysis","Spectroscopy /Instrumentation/Analytical Sciences
Journal title
JOURNAL OF CHROMATOGRAPHY A
ISSN journal
0021-9673 → ACNP
Volume
853
Issue
1-2
Year of publication
1999
Pages
151 - 158
Database
ISI
SICI code
0021-9673(19990820)853:1-2<151:CSBOTC>2.0.ZU;2-1
Abstract
The inner walls of 50 mu m fused-silica capillaries are etched by ammonium hydrogendifluoride and then modified by the silanization/hydrosilation meth od with a chiral selector. Three different types of selectors were evaluate d: lactone, beta-cyclodexhin and naphthylethylamine. Each of the bonded chi ral stationary phases provided at least partial separation for one type of racemic solute. These results confirm that bonded organic moieties on the e tched inner wall of a capillary can provided sufficient solute-bonded phase interactions to influence the retention of molecules driven through a capi llary by electroosmosis or a combination of electroosmosis and electrophore tic mobility. (C) 1999 Elsevier Science B.V. All rights reserved.