Three new alkaloids-griffithazanone A (1), griffithdione (2), and griffithi
nam (3)-were isolated from the roots of Goniothalamus griffithii, along wit
h six known compounds, 4-methyl-2,9, 10-(2H)-1-azaanthracenetrione (4), vel
utinam, aristololactam BI, aristololactam BII, aristololactam AII, and norc
epharanone B. Their structures were elucidated on the basis of spectral and
chemical methods. The absolute configuration of griffithazanone A (1) was
determined by the preparation of Mosher's esters.