Synthesis of new pyrazolo[4,3-c]quinolin-3-one derivatives and some oxazolo[4,5-c]quinoline-2,4-diones

Citation
L. Ismaili et al., Synthesis of new pyrazolo[4,3-c]quinolin-3-one derivatives and some oxazolo[4,5-c]quinoline-2,4-diones, J HETERO CH, 36(3), 1999, pp. 719-722
Citations number
17
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
JOURNAL OF HETEROCYCLIC CHEMISTRY
ISSN journal
0022-152X → ACNP
Volume
36
Issue
3
Year of publication
1999
Pages
719 - 722
Database
ISI
SICI code
0022-152X(199905/06)36:3<719:SONPDA>2.0.ZU;2-1
Abstract
The new pyrazolo[4,3-c]quinolin-3-one derivatives 3a-c and 6a-c were prepar ed by the following three steps: first the preparation of ethyl 4-hydroxyqu inoline-3-carboxylate derivatives 1 and 4 by reaction of isatoic anhydrides and ethyl malonate and ethyl acetoacetate respectively, then chloration of 1 and 4 with phosphorus oxychloride to give 2 and 5 and finally the conden sation of 2 and 5 with hydrazine and its derivatives, In addition, the succ essful synthesis of oxazolo[4,5-c]quinoline-2,4-diones 9a-f are reported.