Ovarian mucinous cystadenocarcinoma with yolk sac tumor in a 71-year-old woman

Citation
T. Arai et al., Ovarian mucinous cystadenocarcinoma with yolk sac tumor in a 71-year-old woman, INT J GYN P, 18(3), 1999, pp. 277-280
Citations number
14
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Reproductive Medicine
Journal title
INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY
ISSN journal
0277-1691 → ACNP
Volume
18
Issue
3
Year of publication
1999
Pages
277 - 280
Database
ISI
SICI code
0277-1691(199907)18:3<277:OMCWYS>2.0.ZU;2-U
Abstract
An ovarian mucinous cystadenocarcinoma admired with a component of yolk sac turner was encountered in a 71-year-old woman, the first such tumor to be reported. The preoperative serum level of alpha-fetoprotein was elevated (5 5.6 ng/mL). A right ovarian cystic tumor, 8 cm in maximal dimension, was re moved and found to have a solid component. Microscopically, the cystic lesi on was a mucinous cystadenocarcinoma, whereas the solid portion was typical yolk sac tumor with microcystic, reticular, and labyrinthine patterns. Sch iller-Duval bodies, scattered giant cells with bizarre nuclei, and intracel lular and extracellular hyaline globules. There was no evidence of other ge rm cell tumor components. Yolk sac tumor showed positive reactions for alph a-fetoprotein, carcinoembryonic antigen, and alpha-1-antitrypsin but was ne gative for CA125, CA19-9, and human chorionic gonadotrophin. The patient di ed of recurrent tumor 6 months postoperatively without response to combinat ion chemotherapy.