Young age as a prognostic factor in cervical cancer: Results of a population-based study

Brewster, WR DiSaia, PJ Monk, BJ Ziogas, A Yamada, SD Anton-Culver, H

Wr. Brewster et al., Young age as a prognostic factor in cervical cancer: Results of a population-based study, AM J OBST G, 180(6), 1999, pp. 1464-1467

11

INGLESE

Article

Reproductive Medicine","da verificare

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

0002-9378 → ACNP

180

6

1999

1

1464 - 1467

ISI

0002-9378(199906)180:6<1464:YAAAPF>2.0.ZU;2-F

OBJECTIVE: Our goal was to use population-based data to determine the diffe rence in 5-year survival in women diagnosed with cervical cancer between th ose aged 18-34 years and those aged 40-60 years. STUDY DESIGN: The SEER (Surveillance, Epidemiology, and End Results) public -use database, 1973-1994, was used for this investigation. Only subjects wi th cervical carcinoma diagnosed between 1988 and 1990 were included. Subjec ts were stratified on age at diagnosis (<35 years or 40-60 years), clinical stager histologic type, race-ethnicity, and grade. RESULTS: Two thousand cases of invasive cervical cancer were identified. Th e younger subgroup of pa patients was diagnosed with earlier-stage disease more frequently than the older group (P=.0001). When adjustments were made for nan-cervical cancer causes of death, there was no difference in 5-year survival between the 2 cohorts. African American women had a poorer 5-year survival (P=.02) CONCLUSION: There was no overall difference in survival between the 2 cohor ts when appropriate adjustments were made for cause of death and for stage, histologic type, and grade of disease.