Synthesis and stereochemistry of beta-aryl-beta-haloacroleins: useful intermediates for the preparation of (Z) and (E)-2-en-4-yne-carbaldehydes and for the synthesis of rubrolides

Citation
D. Prim et al., Synthesis and stereochemistry of beta-aryl-beta-haloacroleins: useful intermediates for the preparation of (Z) and (E)-2-en-4-yne-carbaldehydes and for the synthesis of rubrolides, J CHEM S P2, (6), 1999, pp. 1175-1180
Citations number
33
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2
ISSN journal
0300-9580 → ACNP
Issue
6
Year of publication
1999
Pages
1175 - 1180
Database
ISI
SICI code
0300-9580(199906):6<1175:SASOBU>2.0.ZU;2-0
Abstract
The synthesis of alpha-substituted beta-aryl-beta-haloacroleins by two diff erent pathways is presented. The determination of their stereochemistry by NOE experiments is reported for the first time. Furthermore, we describe th e preparation of 2-en-4-ynecarbaldehydes and access to rubrolide derivative s from beta-aryl-beta-haloacroleins.