Yc. Song et al., Synthesis and anti-cancer activities of a pair of enantiomeric gold(I) complexes containing sulfanyl-substituted P-stereogenic phosphines, TETRAHEDR-A, 10(8), 1999, pp. 1433-1436
A pair of enantiomeric gold(I) complexes containing enantiomerically pure 2
,3-dimethyl-7-pheny1-5-(phenylsulfanyl)-7-(R/S)-phosphabicyclo[2.2.1]hept-2
-ene has been prepared and in vitro cytotoxicity tests showed that both the
enantiomers are relatively nontoxic against healthy lymphocytes, but are h
ighly potent against suspension and monolayer human tumor cell lines. (C) 1
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