Asymmetric synthesis of L-azetidine-2-carboxylic acid and 3-substituted congeners - Conformationally constrained analogs of phenylalanine, naphthylalanine, and leucine

Citation
S. Hanessian et al., Asymmetric synthesis of L-azetidine-2-carboxylic acid and 3-substituted congeners - Conformationally constrained analogs of phenylalanine, naphthylalanine, and leucine, BIOORG MED, 9(10), 1999, pp. 1437-1442
Citations number
41
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960-894X → ACNP
Volume
9
Issue
10
Year of publication
1999
Pages
1437 - 1442
Database
ISI
SICI code
0960-894X(19990517)9:10<1437:ASOLAA>2.0.ZU;2-R
Abstract
Enantiopure L-azetidine-2-carboxylic acid, the (3R)-phenyl, (3R)-naphthyl a nd (3S)-isopropyl analogs were prepared based on a zinc-mediated asymmetric addition of allylic halides to the camphor sultam derivative of glyoxylic acid O-benzyl oxime. (C) 1999 Elsevier Science Ltd. All rights reserved.