Fetal trisomy 10 mosaicism: Ultrasound, cytogenetic and morphologic findings in early pregnancy

Citation
H. Knoblauch et al., Fetal trisomy 10 mosaicism: Ultrasound, cytogenetic and morphologic findings in early pregnancy, PRENAT DIAG, 19(4), 1999, pp. 379-382
Citations number
14
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Reproductive Medicine","Medical Research Diagnosis & Treatment
Journal title
PRENATAL DIAGNOSIS
ISSN journal
0197-3851 → ACNP
Volume
19
Issue
4
Year of publication
1999
Pages
379 - 382
Database
ISI
SICI code
0197-3851(199904)19:4<379:FT1MUC>2.0.ZU;2-9
Abstract
We report the ultrasound, cytogenetic and morphologic findings in a case of trisomy 10 mosaicism prenatally detected by chorionic villus sampling (CVS ). CVS sampling was carried out at the 13th week of gestation because of ul trasound diagnosis of hydrops fetalis and hygroma colli. Trisomy 10 mosaici sm was diagnosed in cells from the cytotrophoblast (short-term culture) and the chorionic villus core (long-term culture). Fetal mosaicism was confirm ed after termination of pregnancy in umbilical cord cells, placenta and fet al skin fibroblasts. Copyright (C) 1999 John Wiley & Sons, Ltd.