Corynebacterium sundsvallense sp. nov., from human clinical specimens

Collins, MD Bernard, KA Hutson, RA Sjoden, B Nyberg, A Falsen, E

Md. Collins et al., Corynebacterium sundsvallense sp. nov., from human clinical specimens, INT J SY B, 49, 1999, pp. 361-366

21

INGLESE

Article

Microbiology

INTERNATIONAL JOURNAL OF SYSTEMATIC BACTERIOLOGY

0020-7713 → ACNP

49

1999

2

361 - 366

ISI

0020-7713(199904)49:<361:CSSNFH>2.0.ZU;2-R

Three strains of a previously undescribed catalase-positive non-lipophilic coryneform bacterium isolated from human clinical specimens were characteri zed by phenotypic and molecular taxonomic methods. Morphologically the unkn own bacterium consisted of pleomorphic rods, some of which displayed bulges /knobs at their ends. All three strains were similar in that they produced acid from fructose, glucose, maltose and sucrose and were urease-positive. Chemotaxonomic investigations revealed the presence of mesa-diaminopimelic acid and short-chain mycolic acids consistent with the genus Corynebacteriu m sensu stricto. Comparative 16S rRNA gene sequencing showed that the three strains are genealogically highly related and constitute a new subline wit hin the genus Corynebacterium, displaying >3% sequence divergence with reco gnized species. The unknown bacterium was distinguished from currently vali dly published Corynebacterium species by phenotypic tests, including electr ophoretic analysis of whole-cell proteins. Based on phylogenetic and phenot ypic evidence, it is proposed that the unknown bacterium from clinical spec imens be classified as Corynebacterium sundsvallense sp. nov. The type stra in is CCUG 36622(T).