S. Jakovljevic et al., Results of renal ultrasonography performed before and during administration of saline (0.9% NaCl) solution to induce diuresis in dogs without evidence of renal disease, AM J VET RE, 60(4), 1999, pp. 405-409
Objective-To evaluate the effect of saline (0.9% NaCl) solution administere
d IV to induce diuresis on 15 dimensional variables of the kidneys, size of
renal pelvis, and diameter of the cranial part of the ureters.
Animals-25 dogs without evidence of renal disease that were undergoing chem
otherapy for various neoplasms. Procedure-The kidneys, cranial aspect of th
e ureters, and trigone area of the urinary bladder of each dog were examine
d ultrasonographically before and during IV administration of saline soluti
on (2.7 to 18.8 ml/kg of body weight/h).
Results-Ultrasonography revealed unilateral and bilateral pyelectasis durin
g diuresis in 16 of 23 (70%) dogs but unilateral pyelectasis in only 1 dog
before diuresis. Unilateral pyelectasis during diuresis was observed in 11
of 16(69%) dogs. Pyelectasis during diuresis was categorized as slight in 1
5 of 21 (71%) kidneys. Degree of pyelectasis during diuresis was not identi
cal in both kidneys of 13 of 16 (81%) dogs. Diuresis did not induce uretere
ctasis, and it did not cause changes in 15 dimensional variables of the kid
Conclusions-In nonsedated, nonazotemic dogs, IV administration of saline so
lution to induce diuresis may cause slight pyelectasis without evidence of
Clinical Relevance-When dilatation of the cranial part of the ureter is > 2
mm at the same time that ipsilateral pyelectasis is detected during ultras
onographic examination of the urinary tract system of a nonsedated, nonazot
emic dog receiving IV administration of saline solution to induce diuresis,
additional examinations are recommended to determine the possibility of ea
rly obstructive nephropathy or pyelonephritis.